ENSG00000105270


Homo sapiens

Features
Gene ID: ENSG00000105270
  
Biological name :CLIP3
  
Synonyms : CAP-Gly domain containing linker protein 3 / CLIP3 / Q96DZ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.12
Gene start: 36014660
Gene end: 36033343
  
Corresponding Affymetrix probe sets: 212358_at (Human Genome U133 Plus 2.0 Array)   235243_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000353732
Ensembl peptide - ENSP00000466026
Ensembl peptide - ENSP00000466832
Ensembl peptide - ENSP00000468689
NCBI entrez gene - 25999     See in Manteia.
OMIM - 607382
RefSeq - NM_001199570
RefSeq - NM_015526
RefSeq Peptide - NP_001186499
RefSeq Peptide - NP_056341
swissprot - Q96DZ5
swissprot - K7ESF3
Ensembl - ENSG00000105270
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clip3ENSDARG00000054456Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLIP4 / Q8N3C7 / CAP-Gly domain containing linker protein family member 4ENSG0000011529556
CLIP1 / P30622 / CAP-Gly domain containing linker protein 1ENSG0000013077919
CLIP2 / Q9UDT6 / CAP-Gly domain containing linker protein 2ENSG0000010666518
CEP350 / Q5VT06 / centrosomal protein 350ENSG0000013583715
TBCB / Q99426 / tubulin folding cofactor BENSG0000010525410
DCTN1 / Q14203 / dynactin subunit 1ENSG000002048439
AC006030.1ENSG000002643240


Protein motifs (from Interpro)
Interpro ID Name
 IPR000938  CAP Gly-rich domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR036859  CAP Gly-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation ISS
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0010828 positive regulation of glucose transmembrane transport ISS
 biological_processGO:0018230 peptidyl-L-cysteine S-palmitoylation IMP
 biological_processGO:0031115 negative regulation of microtubule polymerization IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0044091 membrane biogenesis IMP
 biological_processGO:0045444 fat cell differentiation ISS
 biological_processGO:0045807 positive regulation of endocytosis IMP
 biological_processGO:0072321 chaperone-mediated protein transport IMP
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005802 trans-Golgi network ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane IDA
 cellular_componentGO:0032588 trans-Golgi network membrane IMP
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0055038 recycling endosome membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IMP
 molecular_functionGO:0035594 ganglioside binding IDA


Pathways (from Reactome)
Pathway description
Regulation of TNFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000083799 CYLD / Q9NQC7 / CYLD lysine 63 deubiquitinase  / reaction / complex






 

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