ENSG00000105698


Homo sapiens

Features
Gene ID: ENSG00000105698
  
Biological name :USF2
  
Synonyms : Q15853 / upstream transcription factor 2, c-fos interacting / USF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35268978
Gene end: 35279821
  
Corresponding Affymetrix probe sets: 202152_x_at (Human Genome U133 Plus 2.0 Array)   214879_x_at (Human Genome U133 Plus 2.0 Array)   215737_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000471775
Ensembl peptide - ENSP00000471511
Ensembl peptide - ENSP00000477020
Ensembl peptide - ENSP00000222305
Ensembl peptide - ENSP00000340633
Ensembl peptide - ENSP00000368429
Ensembl peptide - ENSP00000469364
Ensembl peptide - ENSP00000469585
Ensembl peptide - ENSP00000470081
Ensembl peptide - ENSP00000470277
Ensembl peptide - ENSP00000471099
NCBI entrez gene - 7392     See in Manteia.
OMIM - 600390
RefSeq - XM_017027199
RefSeq - NM_001321150
RefSeq - NM_003367
RefSeq - NM_207291
RefSeq - XM_005259197
RefSeq - XM_011527260
RefSeq - XM_011527261
RefSeq Peptide - NP_001308079
RefSeq Peptide - NP_003358
RefSeq Peptide - NP_997174
swissprot - M0QY46
swissprot - M0QYU7
swissprot - M0QZ39
swissprot - M0R1C6
swissprot - V9GYR5
swissprot - Q15853
swissprot - B4DLJ1
swissprot - M0QXT0
Ensembl - ENSG00000105698
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usf2ENSDARG00000020228Danio rerio
 Usf2ENSMUSG00000058239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USF1 / P22415 / upstream transcription factor 1ENSG0000015877341


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000430 regulation of transcription from RNA polymerase II promoter by glucose IC
 biological_processGO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IMP
 biological_processGO:0007595 lactation IEA
 biological_processGO:0019086 late viral transcription IC
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0055088 lipid homeostasis ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043425 bHLH transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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