ENSG00000158773


Homo sapiens

Features
Gene ID: ENSG00000158773
  
Biological name :USF1
  
Synonyms : P22415 / upstream transcription factor 1 / USF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 161039251
Gene end: 161045977
  
Corresponding Affymetrix probe sets: 231768_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356998
Ensembl peptide - ENSP00000356999
Ensembl peptide - ENSP00000435671
Ensembl peptide - ENSP00000435005
Ensembl peptide - ENSP00000433041
Ensembl peptide - ENSP00000432533
Ensembl peptide - ENSP00000357000
NCBI entrez gene - 7391     See in Manteia.
OMIM - 191523
RefSeq - NM_007122
RefSeq - NM_207005
RefSeq - NM_001276373
RefSeq Peptide - NP_001263302
RefSeq Peptide - NP_009053
RefSeq Peptide - NP_996888
swissprot - E9PQA2
swissprot - P22415
swissprot - E9PME6
swissprot - E9PJ52
swissprot - B1AQP1
swissprot - A0A0S2Z4U5
swissprot - H0YD59
Ensembl - ENSG00000158773
  
Related genetic diseases (OMIM): 602491 - {Hyperlipidemia, familial combined, susceptibility to}, 602491

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usf1ENSDARG00000041689Danio rerio
 usf1lENSDARG00000014463Danio rerio
 Usf1ENSMUSG00000026641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USF2 / Q15853 / upstream transcription factor 2, c-fos interactingENSG0000010569846


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000430 regulation of transcription from RNA polymerase II promoter by glucose IC
 biological_processGO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose ISS
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0009411 response to UV ISS
 biological_processGO:0019086 late viral transcription IDA
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0042593 glucose homeostasis TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045990 carbon catabolite regulation of transcription TAS
 biological_processGO:0051918 negative regulation of fibrinolysis IC
 biological_processGO:0055088 lipid homeostasis IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0016589 NURF complex IDA
 cellular_componentGO:0048188 Set1C/COMPASS complex IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity TAS
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043425 bHLH transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr