ENSG00000107014


Homo sapiens

Features
Gene ID: ENSG00000107014
  
Biological name :RLN2
  
Synonyms : P04090 / relaxin 2 / RLN2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p24.1
Gene start: 5299868
Gene end: 5304969
  
Corresponding Affymetrix probe sets: 214519_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371040
Ensembl peptide - ENSP00000399616
NCBI entrez gene - 6019     See in Manteia.
OMIM - 179740
RefSeq - NM_005059
RefSeq - NM_134441
RefSeq Peptide - NP_005050
RefSeq Peptide - NP_604390
swissprot - P04090
swissprot - H0Y5M9
Ensembl - ENSG00000107014
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Rln1ENSMUSG00000039097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RLN1 / P04808 / relaxin 1ENSG0000010701882


Protein motifs (from Interpro)
Interpro ID Name
 IPR016179  Insulin-like
 IPR022352  Insulin family
 IPR022353  Insulin, conserved site
 IPR022421  Relaxin
 IPR036438  Insulin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007565 female pregnancy TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IDA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0050790 regulation of catalytic activity IDA
 cellular_componentGO:0005576 extracellular region TAS
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Relaxin receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000133105 RXFP2 / Q8WXD0 / relaxin/insulin like family peptide receptor 2  / reaction / complex
 ENSG00000107014 RLN2 / P04090 / relaxin 2  / complex
 ENSG00000171509 RXFP1 / Q9HBX9 / relaxin/insulin like family peptide receptor 1  / complex / reaction






 

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