ENSG00000107317


Homo sapiens

Features
Gene ID: ENSG00000107317
  
Biological name :PTGDS
  
Synonyms : P41222 / prostaglandin D2 synthase / PTGDS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.3
Gene start: 136975092
Gene end: 136981742
  
Corresponding Affymetrix probe sets: 211663_x_at (Human Genome U133 Plus 2.0 Array)   211748_x_at (Human Genome U133 Plus 2.0 Array)   212187_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392692
Ensembl peptide - ENSP00000491730
Ensembl peptide - ENSP00000397468
Ensembl peptide - ENSP00000360687
Ensembl peptide - ENSP00000392633
NCBI entrez gene - 5730     See in Manteia.
OMIM - 176803
RefSeq - NM_000954
RefSeq Peptide - NP_000945
swissprot - H0Y4L4
swissprot - H0Y5A1
swissprot - P41222
swissprot - A0A1W2PPU3
swissprot - Q5SQ11
swissprot - A0A024R8G3
Ensembl - ENSG00000107317
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lcn15ENSDARG00000067851Danio rerio
 ptgdsaENSDARG00000069439Danio rerio
 ptgdsb.1ENSDARG00000027088Danio rerio
 ptgdsb.2ENSDARG00000071626Danio rerio
 zgc:153704ENSDARG00000045979Danio rerio
 PTGDSENSGALG00000030886Gallus gallus
 PtgdsENSMUSG00000015090Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL807752.7ENSG00000284341100


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002345  Lipocalin
 IPR002972  Prostaglandin D synthase
 IPR012674  Calycin
 IPR022272  Lipocalin family conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process ISS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006693 prostaglandin metabolic process IEA
 biological_processGO:0019371 cyclooxygenase pathway TAS
 biological_processGO:0045187 regulation of circadian sleep/wake cycle, sleep ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004667 prostaglandin-D synthase activity TAS
 molecular_functionGO:0005501 retinoid binding ISS
 molecular_functionGO:0005504 fatty acid binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0036094 small molecule binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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