ENSG00000108018


Homo sapiens

Features
Gene ID: ENSG00000108018
  
Biological name :SORCS1
  
Synonyms : Q8WY21 / SORCS1 / sortilin related VPS10 domain containing receptor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q25.1
Gene start: 106573663
Gene end: 107164534
  
Corresponding Affymetrix probe sets: 1556891_at (Human Genome U133 Plus 2.0 Array)   228194_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358712
Ensembl peptide - ENSP00000345964
Ensembl peptide - ENSP00000407769
Ensembl peptide - ENSP00000478065
Ensembl peptide - ENSP00000477888
Ensembl peptide - ENSP00000263054
NCBI entrez gene - 114815     See in Manteia.
OMIM - 606283
RefSeq - XM_017015618
RefSeq - NM_001013031
RefSeq - NM_001206569
RefSeq - NM_001206570
RefSeq - NM_001206571
RefSeq - NM_001206572
RefSeq - NM_052918
RefSeq - XM_011539199
RefSeq - XM_011539201
RefSeq - XM_017015614
RefSeq - XM_017015615
RefSeq - XM_017015616
RefSeq - XM_017015617
RefSeq Peptide - NP_001193500
RefSeq Peptide - NP_001193501
RefSeq Peptide - NP_443150
RefSeq Peptide - NP_001013049
RefSeq Peptide - NP_001193498
RefSeq Peptide - NP_001193499
swissprot - Q8WY21
swissprot - A0A087WTQ9
swissprot - H7C2U3
swissprot - A0A0A0MRC2
swissprot - X6R7D6
swissprot - A0A087WTI0
Ensembl - ENSG00000108018
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017711.1ENSDARG00000112034Danio rerio
 SORCS1ENSGALG00000008465Gallus gallus
 Sorcs1ENSMUSG00000043531Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UPU3 / SORCS3 / sortilin related VPS10 domain containing receptor 3ENSG0000015639564
Q96PQ0 / SORCS2 / sortilin related VPS10 domain containing receptor 2ENSG0000018498543
SORL1 / Q92673 / sortilin related receptor 1ENSG0000013764223
SORT1 / Q99523 / sortilin 1ENSG0000013424316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR006581  VPS10
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007218 neuropeptide signaling pathway NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008188 neuropeptide receptor activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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