ENSG00000156395


Homo sapiens

Features
Gene ID: ENSG00000156395
  
Biological name :SORCS3
  
Synonyms : Q9UPU3 / SORCS3 / sortilin related VPS10 domain containing receptor 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q25.1
Gene start: 104641101
Gene end: 105265235
  
Corresponding Affymetrix probe sets: 215522_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358713
Ensembl peptide - ENSP00000358715
Ensembl peptide - ENSP00000376876
NCBI entrez gene - 22986     See in Manteia.
OMIM - 606285
RefSeq - XM_011539542
RefSeq - NM_014978
RefSeq Peptide - NP_055793
swissprot - Q5CAJ2
swissprot - Q9UPU3
Ensembl - ENSG00000156395
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SORCS3ENSDARG00000103535Danio rerio
 sorcs3bENSDARG00000077349Danio rerio
 SORCS3ENSGALG00000008434Gallus gallus
 Q8VI51ENSMUSG00000063434Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WY21 / SORCS1 / sortilin related VPS10 domain containing receptor 1ENSG0000010801861
Q96PQ0 / SORCS2 / sortilin related VPS10 domain containing receptor 2ENSG0000018498540
SORL1 / Q92673 / sortilin related receptor 1ENSG0000013764222
SORT1 / Q99523 / sortilin 1ENSG0000013424315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR006581  VPS10
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007218 neuropeptide signaling pathway NAS
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:1900452 regulation of long term synaptic depression IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008188 neuropeptide receptor activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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