ENSG00000184985


Homo sapiens

Features
Gene ID: ENSG00000184985
  
Biological name :SORCS2
  
Synonyms : Q96PQ0 / SORCS2 / sortilin related VPS10 domain containing receptor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p16.1
Gene start: 7192538
Gene end: 7742836
  
Corresponding Affymetrix probe sets: 228720_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424194
Ensembl peptide - ENSP00000329124
Ensembl peptide - ENSP00000422185
NCBI entrez gene - 57537     See in Manteia.
OMIM - 606284
RefSeq - XM_017008481
RefSeq - XM_005247987
RefSeq - XM_011513514
RefSeq - XM_011513515
RefSeq - XM_011513516
RefSeq - NM_020777
RefSeq Peptide - NP_065828
swissprot - H0Y9I2
swissprot - B5MED8
swissprot - Q96PQ0
Ensembl - ENSG00000184985
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sorcs2ENSDARG00000077465Danio rerio
 SORCS2ENSGALG00000015554Gallus gallus
 Q9EPR5ENSMUSG00000029093Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WY21 / SORCS1 / sortilin related VPS10 domain containing receptor 1ENSG0000010801843
Q9UPU3 / SORCS3 / sortilin related VPS10 domain containing receptor 3ENSG0000015639542
SORL1 / Q92673 / sortilin related receptor 1ENSG0000013764223
SORT1 / Q99523 / sortilin 1ENSG0000013424317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR006581  VPS10
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR022409  PKD/Chitinase domain
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007218 neuropeptide signaling pathway NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008188 neuropeptide receptor activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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