ENSG00000108039


Homo sapiens

Features
Gene ID: ENSG00000108039
  
Biological name :XPNPEP1
  
Synonyms : Q9NQW7 / XPNPEP1 / X-prolyl aminopeptidase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q25.1
Gene start: 109864766
Gene end: 109923553
  
Corresponding Affymetrix probe sets: 208453_s_at (Human Genome U133 Plus 2.0 Array)   209045_at (Human Genome U133 Plus 2.0 Array)   236239_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358697
Ensembl peptide - ENSP00000410318
Ensembl peptide - ENSP00000421566
Ensembl peptide - ENSP00000385388
Ensembl peptide - ENSP00000324011
NCBI entrez gene - 7511     See in Manteia.
OMIM - 602443
RefSeq - NM_001324135
RefSeq - NM_001324136
RefSeq - NM_020383
RefSeq - XM_017016615
RefSeq - NM_001167604
RefSeq - NM_001324128
RefSeq - NM_001324131
RefSeq - NM_001324132
RefSeq - NM_001324133
RefSeq - NM_001324134
RefSeq - XM_011540134
RefSeq - XM_017016613
RefSeq - XM_017016614
RefSeq Peptide - NP_001311062
RefSeq Peptide - NP_001311063
RefSeq Peptide - NP_001311064
RefSeq Peptide - NP_001311065
RefSeq Peptide - NP_065116
RefSeq Peptide - NP_001161076
RefSeq Peptide - NP_001311057
RefSeq Peptide - NP_001311060
RefSeq Peptide - NP_001311061
swissprot - Q5T6H2
swissprot - Q5T6H3
swissprot - Q5T6H7
swissprot - Q9NQW7
Ensembl - ENSG00000108039
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xpnpep1ENSDARG00000029011Danio rerio
 XPNPEP1ENSGALG00000008523Gallus gallus
 Xpnpep1ENSMUSG00000025027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43895 / XPNPEP2 / X-prolyl aminopeptidase 2ENSG0000012212139


Protein motifs (from Interpro)
Interpro ID Name
 IPR000587  Creatinase, N-terminal
 IPR000994  Peptidase M24
 IPR001131  Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site
 IPR029149  Creatinase/Aminopeptidase P/Spt16, N-terminal
 IPR032416  Peptidase M24, C-terminal domain
 IPR033740  Aminopeptidase P
 IPR036005  Creatinase/aminopeptidase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010815 bradykinin catabolic process IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004177 aminopeptidase activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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