ENSG00000108342


Homo sapiens

Features
Gene ID: ENSG00000108342
  
Biological name :CSF3
  
Synonyms : colony stimulating factor 3 / CSF3 / P09919
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.1
Gene start: 40015361
Gene end: 40017813
  
Corresponding Affymetrix probe sets: 207442_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464421
Ensembl peptide - ENSP00000225474
Ensembl peptide - ENSP00000327766
Ensembl peptide - ENSP00000377704
Ensembl peptide - ENSP00000377705
Ensembl peptide - ENSP00000462991
Ensembl peptide - ENSP00000464157
NCBI entrez gene - 1440     See in Manteia.
OMIM - 138970
RefSeq - NM_000759
RefSeq - NM_172219
RefSeq - NM_172220
RefSeq - NM_001178147
RefSeq Peptide - NP_000750
RefSeq Peptide - NP_757373
RefSeq Peptide - NP_757374
RefSeq Peptide - NP_001171618
swissprot - Q8N4W3
swissprot - J3KTH8
swissprot - J3QRD4
swissprot - J3QRX2
swissprot - P09919
swissprot - Q6FH65
Ensembl - ENSG00000108342
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CSF3ENSGALG00000030907Gallus gallus
 Csf3ENSMUSG00000038067Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR030473  Interleukin-6/GCSF/MGF, conserved site
 IPR030474  Interleukin-6/GCSF/MGF


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway NAS
 biological_processGO:0030223 neutrophil differentiation IBA
 biological_processGO:0030225 macrophage differentiation IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IDA
 biological_processGO:0030851 granulocyte differentiation NAS
 biological_processGO:0032092 positive regulation of protein binding IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0042993 obsolete positive regulation of transcription factor import into nucleus IDA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045639 positive regulation of myeloid cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0061515 myeloid cell development IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071345 cellular response to cytokine stimulus IDA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005130 granulocyte colony-stimulating factor receptor binding TAS
 molecular_functionGO:0008083 growth factor activity IBA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Other interleukin signaling
Interleukin-10 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108342 CSF3 / P09919 / colony stimulating factor 3  / complex
 ENSG00000119535 CSF3R / Q99062 / colony stimulating factor 3 receptor  / reaction / complex






 

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