ENSG00000108828


Homo sapiens

Features
Gene ID: ENSG00000108828
  
Biological name :VAT1
  
Synonyms : Q99536 / VAT1 / vesicle amine transport 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.31
Gene start: 43014605
Gene end: 43025123
  
Corresponding Affymetrix probe sets: 208626_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468146
Ensembl peptide - ENSP00000468621
Ensembl peptide - ENSP00000468401
Ensembl peptide - ENSP00000347872
Ensembl peptide - ENSP00000408553
Ensembl peptide - ENSP00000465239
Ensembl peptide - ENSP00000465946
Ensembl peptide - ENSP00000466322
Ensembl peptide - ENSP00000467131
NCBI entrez gene - 10493     See in Manteia.
OMIM - 604631
RefSeq - NM_006373
RefSeq Peptide - NP_006364
swissprot - K7ENX2
swissprot - K7ER81
swissprot - K7ERT7
swissprot - K7ESA3
swissprot - A0A024R1Z6
swissprot - Q99536
swissprot - K7EJM4
swissprot - K7EM19
Ensembl - ENSG00000108828
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vat1ENSDARG00000056481Danio rerio
 VAT1ENSGALG00000002818Gallus gallus
 Vat1ENSMUSG00000034993Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VAT1L / Q9HCJ6 / vesicle amine transport 1 likeENSG0000017172443
CRYZ / Q08257 / crystallin zetaENSG0000011679126
Q53FA7 / TP53I3 / tumor protein p53 inducible protein 3ENSG0000011512926
MECR / Q9BV79 / mitochondrial trans-2-enoyl-CoA reductaseENSG0000011635322


Protein motifs (from Interpro)
Interpro ID Name
 IPR002364  Quinone oxidoreductase/zeta-crystallin, conserved site
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR020843  Polyketide synthase, enoylreductase domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010637 negative regulation of mitochondrial fusion IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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