ENSG00000115129


Homo sapiens

Features
Gene ID: ENSG00000115129
  
Biological name :TP53I3
  
Synonyms : Q53FA7 / TP53I3 / tumor protein p53 inducible protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p23.3
Gene start: 24077433
Gene end: 24085861
  
Corresponding Affymetrix probe sets: 210609_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000238721
Ensembl peptide - ENSP00000337834
Ensembl peptide - ENSP00000384414
Ensembl peptide - ENSP00000389620
NCBI entrez gene - 9540     See in Manteia.
OMIM - 605171
RefSeq - XM_006712150
RefSeq - NM_001206802
RefSeq - NM_004881
RefSeq - NM_147184
RefSeq - XM_005264650
RefSeq Peptide - NP_004872
RefSeq Peptide - NP_671713
RefSeq Peptide - NP_001193731
swissprot - Q53FA7
swissprot - H7BZH6
Ensembl - ENSG00000115129
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR628323.3ENSDARG00000106158Danio rerio
 TP53I3ENSGALG00000016502Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VAT1 / Q99536 / vesicle amine transport 1ENSG0000010882831
VAT1L / Q9HCJ6 / vesicle amine transport 1 likeENSG0000017172430
CRYZ / Q08257 / crystallin zetaENSG0000011679127
MECR / Q9BV79 / mitochondrial trans-2-enoyl-CoA reductaseENSG0000011635321


Protein motifs (from Interpro)
Interpro ID Name
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR014189  Quinone oxidoreductase PIG3
 IPR020843  Polyketide synthase, enoylreductase domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006739 NADP metabolic process IDA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003960 NADPH:quinone reductase activity EXP
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0048038 quinone binding IDA
 molecular_functionGO:0070402 NADPH binding IDA


Pathways (from Reactome)
Pathway description
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115129 Q53FA7 / TP53I3 / tumor protein p53 inducible protein 3  / complex / reaction






 

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