ENSG00000109272


Homo sapiens

Features
Gene ID: ENSG00000109272
  
Biological name :PF4V1
  
Synonyms : P10720 / PF4V1 / platelet factor 4 variant 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q13.3
Gene start: 73853189
Gene end: 73854155
  
Corresponding Affymetrix probe sets: 207815_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000226524
NCBI entrez gene - 5197     See in Manteia.
OMIM - 173461
RefSeq - NM_002620
RefSeq Peptide - NP_002611
swissprot - P10720
Ensembl - ENSG00000109272
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Pf4ENSMUSG00000029373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PF4 / P02776 / platelet factor 4ENSG0000016373784


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR027222  Platelet factor 4
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0030595 leukocyte chemotaxis IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0008201 heparin binding IBA
 molecular_functionGO:0045236 CXCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Common Pathway of Fibrin Clot Formation
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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