ENSG00000109625


Homo sapiens

Features
Gene ID: ENSG00000109625
  
Biological name :CPZ
  
Synonyms : carboxypeptidase Z / CPZ / Q66K79
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p16.1
Gene start: 8592660
Gene end: 8619759
  
Corresponding Affymetrix probe sets: 211062_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422693
Ensembl peptide - ENSP00000315074
Ensembl peptide - ENSP00000354255
Ensembl peptide - ENSP00000371920
NCBI entrez gene - 8532     See in Manteia.
OMIM - 603105
RefSeq - NM_001014447
RefSeq - NM_001014448
RefSeq - NM_003652
RefSeq Peptide - NP_001014447
RefSeq Peptide - NP_001014448
RefSeq Peptide - NP_003643
swissprot - Q66K79
swissprot - D6RBI5
Ensembl - ENSG00000109625
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpzENSDARG00000075521Danio rerio
 CPZENSGALG00000030209Gallus gallus
 CpzENSMUSG00000036596Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPD / O75976 / carboxypeptidase DENSG0000010858235
CPXM1 / Q96SM3 / carboxypeptidase X, M14 family member 1ENSG0000008888234
CPE / P16870 / carboxypeptidase EENSG0000010947232
CPN1 / P15169 / carboxypeptidase N subunit 1ENSG0000012005431
CPXM2 / Q8N436 / carboxypeptidase X, M14 family member 2ENSG0000012189831
AEBP1 / Q8IUX7 / AE binding protein 1ENSG0000010662431
CPM / P14384 / carboxypeptidase MENSG0000013567824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000834  Peptidase M14, carboxypeptidase A
 IPR008969  Carboxypeptidase-like, regulatory domain superfamily
 IPR020067  Frizzled domain
 IPR034239  Metallocarboxypeptidase Z, carboxypeptidase domain
 IPR036790  Frizzled cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006518 peptide metabolic process IBA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016485 protein processing IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0004181 metallocarboxypeptidase activity TAS
 molecular_functionGO:0004185 serine-type carboxypeptidase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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