ENSG00000135678


Homo sapiens

Features
Gene ID: ENSG00000135678
  
Biological name :CPM
  
Synonyms : carboxypeptidase M / CPM / P14384
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q15
Gene start: 68842197
Gene end: 68971570
  
Corresponding Affymetrix probe sets: 206100_at (Human Genome U133 Plus 2.0 Array)   217557_s_at (Human Genome U133 Plus 2.0 Array)   235019_at (Human Genome U133 Plus 2.0 Array)   235706_at (Human Genome U133 Plus 2.0 Array)   241765_at (Human Genome U133 Plus 2.0 Array)   243403_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447255
Ensembl peptide - ENSP00000448078
Ensembl peptide - ENSP00000448517
Ensembl peptide - ENSP00000449911
Ensembl peptide - ENSP00000450400
Ensembl peptide - ENSP00000339157
Ensembl peptide - ENSP00000446573
Ensembl peptide - ENSP00000446799
Ensembl peptide - ENSP00000447051
Ensembl peptide - ENSP00000447455
NCBI entrez gene - 1368     See in Manteia.
OMIM - 114860
RefSeq - NM_001874
RefSeq - NM_198320
RefSeq - NM_001005502
RefSeq Peptide - NP_001865
RefSeq Peptide - NP_001005502
RefSeq Peptide - NP_938079
swissprot - P14384
swissprot - F8VR29
swissprot - F8VU13
swissprot - F8VVI6
swissprot - F8W111
swissprot - H0YHG6
swissprot - H0YHN7
Ensembl - ENSG00000135678
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpmENSDARG00000011769Danio rerio
 CPMENSGALG00000009945Gallus gallus
 CpmENSMUSG00000020183Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPD / O75976 / carboxypeptidase DENSG0000010858243
CPN1 / P15169 / carboxypeptidase N subunit 1ENSG0000012005438
CPE / P16870 / carboxypeptidase EENSG0000010947237
CPZ / Q66K79 / carboxypeptidase ZENSG0000010962536
CPXM1 / Q96SM3 / carboxypeptidase X, M14 family member 1ENSG0000008888233
CPXM2 / Q8N436 / carboxypeptidase X, M14 family member 2ENSG0000012189831
AEBP1 / Q8IUX7 / AE binding protein 1ENSG0000010662428


Protein motifs (from Interpro)
Interpro ID Name
 IPR000834  Peptidase M14, carboxypeptidase A
 IPR008969  Carboxypeptidase-like, regulatory domain superfamily
 IPR033842  Carboxypeptidase M N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006518 peptide metabolic process IBA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0016485 protein processing IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004180 carboxypeptidase activity TAS
 molecular_functionGO:0004181 metallocarboxypeptidase activity TAS
 molecular_functionGO:0004185 serine-type carboxypeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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