ENSG00000109689


Homo sapiens

Features
Gene ID: ENSG00000109689
  
Biological name :STIM2
  
Synonyms : Q9P246 / STIM2 / stromal interaction molecule 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p15.2
Gene start: 26857678
Gene end: 27025381
  
Corresponding Affymetrix probe sets: 225246_at (Human Genome U133 Plus 2.0 Array)   225250_at (Human Genome U133 Plus 2.0 Array)   234140_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473527
Ensembl peptide - ENSP00000419383
Ensembl peptide - ENSP00000419073
Ensembl peptide - ENSP00000417569
Ensembl peptide - ENSP00000492556
Ensembl peptide - ENSP00000492400
Ensembl peptide - ENSP00000419536
Ensembl peptide - ENSP00000420113
Ensembl peptide - ENSP00000473283
Ensembl peptide - ENSP00000473581
NCBI entrez gene - 57620     See in Manteia.
OMIM - 610841
RefSeq - NM_001169117
RefSeq - NM_020860
RefSeq - NM_001169118
RefSeq Peptide - NP_065911
RefSeq Peptide - NP_001162589
RefSeq Peptide - NP_001162588
swissprot - R4GNC5
swissprot - A0A1W2PRA1
swissprot - A0A1X7SBY3
swissprot - H0Y860
swissprot - H7C5A5
swissprot - H7C5C6
swissprot - H7C5K2
swissprot - Q9P246
swissprot - R4GMP0
swissprot - R4GN82
Ensembl - ENSG00000109689
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stim2aENSDARG00000074867Danio rerio
 stim2bENSDARG00000001776Danio rerio
 STIM2ENSGALG00000014355Gallus gallus
 Stim2ENSMUSG00000039156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STIM1 / Q13586 / stromal interaction molecule 1ENSG000001673238


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR032393  Stromal interaction molecule, Orai1-activating region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002115 store-operated calcium entry IBA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0032237 activation of store-operated calcium channel activity IMP
 biological_processGO:0051928 positive regulation of calcium ion transport IMP
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005246 calcium channel regulator activity IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015279 store-operated calcium channel activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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