ENSG00000112818


Homo sapiens

Features
Gene ID: ENSG00000112818
  
Biological name :MEP1A
  
Synonyms : MEP1A / meprin A subunit alpha / Q16819
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p12.3
Gene start: 46793390
Gene end: 46839782
  
Corresponding Affymetrix probe sets: 206000_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480465
Ensembl peptide - ENSP00000230588
NCBI entrez gene - 4224     See in Manteia.
OMIM - 600388
RefSeq - XM_011514629
RefSeq - NM_005588
RefSeq - XM_011514628
RefSeq Peptide - NP_005579
swissprot - Q16819
swissprot - B7ZL91
Ensembl - ENSG00000112818
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mep1a.1ENSDARG00000029747Danio rerio
 MEP1AENSGALG00000033033Gallus gallus
 Mep1aENSMUSG00000023914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MEP1B / Q16820 / meprin A subunit betaENSG0000014143439
ASTL / Q6HA08 / astacin like metalloendopeptidaseENSG0000018888614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000998  MAM domain
 IPR001506  Peptidase M12A
 IPR002083  MATH/TRAF domain
 IPR006026  Peptidase, metallopeptidase
 IPR008294  Meprin alpha/beta subunit
 IPR008974  TRAF-like
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034038  Meprin peptidase domain
 IPR034301  Meprin alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017090 meprin A complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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