ENSG00000113194


Homo sapiens

Features
Gene ID: ENSG00000113194
  
Biological name :FAF2
  
Synonyms : FAF2 / Fas associated factor family member 2 / Q96CS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.2
Gene start: 176447628
Gene end: 176510074
  
Corresponding Affymetrix probe sets: 212106_at (Human Genome U133 Plus 2.0 Array)   212108_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261942
Ensembl peptide - ENSP00000424146
NCBI entrez gene - 23197     See in Manteia.
OMIM - 616935
RefSeq - NM_014613
RefSeq - XM_011534475
RefSeq Peptide - NP_055428
swissprot - D6RBG6
swissprot - Q96CS3
Ensembl - ENSG00000113194
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 faf2ENSDARG00000052374Danio rerio
 FAF2ENSGALG00000003331Gallus gallus
 Faf2ENSMUSG00000025873Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FAF1 / Q9UNN5 / Fas associated factor 1ENSG0000018510428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001012  UBX domain
 IPR006577  UAS
 IPR009060  UBA-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IMP
 biological_processGO:0034389 lipid particle organization IMP
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IDA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IDA
 molecular_functionGO:0035473 lipase binding IDA
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0055102 lipase inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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