ENSG00000185104


Homo sapiens

Features
Gene ID: ENSG00000185104
  
Biological name :FAF1
  
Synonyms : FAF1 / Fas associated factor 1 / Q9UNN5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 50437028
Gene end: 50960263
  
Corresponding Affymetrix probe sets: 218080_x_at (Human Genome U133 Plus 2.0 Array)   222511_x_at (Human Genome U133 Plus 2.0 Array)   224217_s_at (Human Genome U133 Plus 2.0 Array)   236200_at (Human Genome U133 Plus 2.0 Array)   239749_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360843
Ensembl peptide - ENSP00000434929
Ensembl peptide - ENSP00000379457
NCBI entrez gene - 11124     See in Manteia.
OMIM - 604460
RefSeq - NM_007051
RefSeq - XM_017000136
RefSeq Peptide - NP_008982
swissprot - B3KT28
swissprot - Q9UNN5
swissprot - B1ANM7
Ensembl - ENSG00000185104
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 faf1ENSDARG00000022418Danio rerio
 FAF1ENSGALG00000010536Gallus gallus
 Faf1ENSMUSG00000010517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FAF2 / Q96CS3 / Fas associated factor family member 2ENSG0000011319419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001012  UBX domain
 IPR006577  UAS
 IPR029071  Ubiquitin-like domain superfamily
 IPR033043  FAS-associated factor 1, UBX domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007253 cytoplasmic sequestering of NF-kappaB IMP
 biological_processGO:0008219 cell death IEA
 biological_processGO:0010942 positive regulation of cell death IDA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0031334 positive regulation of protein complex assembly IMP
 biological_processGO:0042176 regulation of protein catabolic process IMP
 biological_processGO:0043065 positive regulation of apoptotic process NAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031265 CD95 death-inducing signaling complex NAS
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019887 protein kinase regulator activity NAS
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0031072 heat shock protein binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IDA
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0051059 NF-kappaB binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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