ENSG00000113569


Homo sapiens

Features
Gene ID: ENSG00000113569
  
Biological name :NUP155
  
Synonyms : nucleoporin 155 / NUP155 / O75694
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: p13.2
Gene start: 37288137
Gene end: 37371181
  
Corresponding Affymetrix probe sets: 206550_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000231498
Ensembl peptide - ENSP00000423484
Ensembl peptide - ENSP00000422019
Ensembl peptide - ENSP00000371265
NCBI entrez gene - 9631     See in Manteia.
OMIM - 606694
RefSeq - XM_011514165
RefSeq - NM_001278312
RefSeq - NM_004298
RefSeq - NM_153485
RefSeq Peptide - NP_004289
RefSeq Peptide - NP_001265241
RefSeq Peptide - NP_705618
swissprot - O75694
swissprot - D6RA13
swissprot - E9PF10
swissprot - A0A024R071
Ensembl - ENSG00000113569
  
Related genetic diseases (OMIM): 615770 - ?Atrial fibrillation 15, 615770
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup155ENSDARG00000001777Danio rerio
 NUP155ENSGALG00000003688Gallus gallus
 Nup155ENSMUSG00000022142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004870  Nucleoporin, Nup155-like
 IPR007187  Nucleoporin, Nup133/Nup155-like, C-terminal
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR014908  Nucleoporin, Nup133/Nup155-like, N-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006405 RNA export from nucleus IBA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0006998 nuclear envelope organization IDA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0036228 protein localization to nuclear inner membrane IBA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:0086014 atrial cardiac muscle cell action potential IEA
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0044611 nuclear pore inner ring IBA
 molecular_functionGO:0005215 transporter activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017056 structural constituent of nuclear pore IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000007 Autosomal recessive inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators]
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 HP:0004749 Atrial fibrillation or flutter 
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 HP:0005110 Atrial fibrillation 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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