ENSMUSG00000022142


Mus musculus

Features
Gene ID: ENSMUSG00000022142
  
Biological name :Nup155
  
Synonyms : Nuclear pore complex protein Nup155 / Nup155 / Q99P88
  
Possible biological names infered from orthology : nucleoporin 155 / O75694
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: A1
Gene start: 8109273
Gene end: 8161247
  
Corresponding Affymetrix probe sets: 10422854 (MoGene1.0st)   1418727_at (Mouse Genome 430 2.0 Array)   1444342_at (Mouse Genome 430 2.0 Array)   1445136_at (Mouse Genome 430 2.0 Array)   1449200_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128819
Ensembl peptide - ENSMUSP00000155093
NCBI entrez gene - 170762     See in Manteia.
MGI - MGI:2181182
RefSeq - XM_006519972
RefSeq - NM_133227
RefSeq Peptide - NP_573490
swissprot - Q99P88
Ensembl - ENSMUSG00000022142
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup155ENSDARG00000001777Danio rerio
 NUP155ENSGALG00000003688Gallus gallus
 NUP155ENSG00000113569Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004870  Nucleoporin, Nup155-like
 IPR007187  Nucleoporin, Nup133/Nup155-like, C-terminal
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR014908  Nucleoporin, Nup133/Nup155-like, N-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
 biological_processGO:0006406 mRNA export from nucleus IMP
 biological_processGO:0006606 protein import into nucleus IMP
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0006998 nuclear envelope organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0036228 protein localization to nuclear inner membrane IBA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0086014 atrial cardiac muscle cell action potential IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0044611 nuclear pore inner ring IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017056 structural constituent of nuclear pore IEA


Pathways (from Reactome)
Pathway description
Transport of Mature mRNA derived from an Intron-Containing Transcript
Regulation of Glucokinase by Glucokinase Regulatory Protein
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003137 abnormal impulse conducting system conduction "anomaly in the impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart" [hdene:Howard Dene , Mouse Genome Informatics Curator, J:92050, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

 MP:0008543 atrial fibrillation "asynchronous contraction or quivering of individual cardiac muscle fibers in the atria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

 MP:0010504 abnormal RR interval "anomaly in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

 MP:0010510 absent P wave "absence of the P wave which represents atrial depolarization and corresponds to electrical impulses rather than mechanical atria contractions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Seletm2Hyn/Seletm2Hyn
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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