ENSG00000114455


Homo sapiens

Features
Gene ID: ENSG00000114455
  
Biological name :HHLA2
  
Synonyms : HERV-H LTR-associating 2 / HHLA2 / Q9UM44
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.13
Gene start: 108296490
Gene end: 108378285
  
Corresponding Affymetrix probe sets: 220812_s_at (Human Genome U133 Plus 2.0 Array)   234673_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418797
Ensembl peptide - ENSP00000418345
Ensembl peptide - ENSP00000419207
Ensembl peptide - ENSP00000482187
Ensembl peptide - ENSP00000420622
Ensembl peptide - ENSP00000419940
Ensembl peptide - ENSP00000419911
Ensembl peptide - ENSP00000350402
Ensembl peptide - ENSP00000417856
Ensembl peptide - ENSP00000418174
Ensembl peptide - ENSP00000418284
NCBI entrez gene - 11148     See in Manteia.
OMIM - 604371
RefSeq - XM_017005642
RefSeq - NM_001282556
RefSeq - NM_001282557
RefSeq - NM_001282558
RefSeq - NM_001282559
RefSeq - NM_007072
RefSeq - XM_005247080
RefSeq - XM_011512362
RefSeq - XM_011512363
RefSeq - XM_011512364
RefSeq - XM_011512367
RefSeq Peptide - NP_001269487
RefSeq Peptide - NP_001269488
RefSeq Peptide - NP_009003
RefSeq Peptide - NP_001269486
RefSeq Peptide - NP_001269485
swissprot - H7C523
swissprot - Q9UM44
swissprot - C9J7D0
swissprot - C9JY43
swissprot - C9JY13
swissprot - C9JD07
swissprot - C9J8J7
Ensembl - ENSG00000114455
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hhla2a.1ENSDARG00000043182Danio rerio
 hhla2a.2ENSDARG00000004763Danio rerio
 hhla2b.1ENSDARG00000088680Danio rerio
 hhla2b.2ENSDARG00000086254Danio rerio
 HHLA2ENSGALG00000022871Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD276 / Q5ZPR3 / CD276 moleculeENSG0000010385515
VTCN1 / Q7Z7D3 / V-set domain containing T cell activation inhibitor 1ENSG0000013425814
ICOSLG / O75144 / inducible T cell costimulator ligandENSG0000016022313
FP565260.3ENSG0000027711713


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IDA
 biological_processGO:0031295 T cell costimulation IDA
 biological_processGO:0042104 positive regulation of activated T cell proliferation IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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