ENSG00000134258


Homo sapiens

Features
Gene ID: ENSG00000134258
  
Biological name :VTCN1
  
Synonyms : Q7Z7D3 / V-set domain containing T cell activation inhibitor 1 / VTCN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p12
Gene start: 117143587
Gene end: 117210960
  
Corresponding Affymetrix probe sets: 219768_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328168
Ensembl peptide - ENSP00000358470
Ensembl peptide - ENSP00000444724
Ensembl peptide - ENSP00000484316
Ensembl peptide - ENSP00000351899
NCBI entrez gene - 79679     See in Manteia.
OMIM - 608162
RefSeq - XM_017002335
RefSeq - NM_001253849
RefSeq - NM_001253850
RefSeq - NM_024626
RefSeq - XM_011542143
RefSeq Peptide - NP_001240779
RefSeq Peptide - NP_078902
RefSeq Peptide - NP_001240778
swissprot - Q5T2L0
swissprot - Q7Z7D3
swissprot - A0A087X1M4
Ensembl - ENSG00000134258
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vtcn1ENSDARG00000078643Danio rerio
 ENSGALG00000014820Gallus gallus
 Vtcn1ENSMUSG00000051076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD276 / Q5ZPR3 / CD276 moleculeENSG0000010385522
HHLA2 / Q9UM44 / HERV-H LTR-associating 2ENSG0000011445521
FP565260.3ENSG0000027711718
ICOSLG / O75144 / inducible T cell costimulator ligandENSG0000016022318


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001562 response to protozoan IEA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0050868 negative regulation of T cell activation IMP
 biological_processGO:0072602 interleukin-4 secretion IEA
 biological_processGO:0072643 interferon-gamma secretion IEA
 biological_processGO:1900042 positive regulation of interleukin-2 secretion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005102 signaling receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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