ENSG00000114541


Homo sapiens

Features
Gene ID: ENSG00000114541
  
Biological name :FRMD4B
  
Synonyms : FERM domain containing 4B / FRMD4B / Q9Y2L6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p14.1
Gene start: 69169990
Gene end: 69542583
  
Corresponding Affymetrix probe sets: 213056_at (Human Genome U133 Plus 2.0 Array)   216131_at (Human Genome U133 Plus 2.0 Array)   216134_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381549
Ensembl peptide - ENSP00000420735
Ensembl peptide - ENSP00000419869
Ensembl peptide - ENSP00000418962
Ensembl peptide - ENSP00000418682
Ensembl peptide - ENSP00000418373
Ensembl peptide - ENSP00000418023
Ensembl peptide - ENSP00000417765
Ensembl peptide - ENSP00000417550
NCBI entrez gene - 23150     See in Manteia.
OMIM - 617467
RefSeq - XM_017005990
RefSeq - XM_017005991
RefSeq - XM_017005992
RefSeq - XM_017005993
RefSeq - XM_017005994
RefSeq - XM_017005995
RefSeq - XM_017005996
RefSeq - XM_017005997
RefSeq - NM_015123
RefSeq - XM_005264723
RefSeq - XM_017005989
RefSeq - XM_005264722
RefSeq Peptide - NP_055938
swissprot - Q9Y2L6
swissprot - C9JYK2
swissprot - C9JBX2
swissprot - C9JAW0
swissprot - C9JA15
swissprot - C9J7M5
swissprot - C9J6Q2
swissprot - H7C550
swissprot - E9PGA7
Ensembl - ENSG00000114541
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frmd4baENSDARG00000074599Danio rerio
 frmd4bbENSDARG00000076496Danio rerio
 FRMD4BENSGALG00000037791Gallus gallus
 Frmd4bENSMUSG00000030064Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FRMD4A / Q9P2Q2 / FERM domain containing 4AENSG0000015147448
Q96HB5 / CCDC120 / coiled-coil domain containing 120ENSG0000014714416
INAVA / Q3KP66 / innate immunity activatorENSG0000016336214


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR021774  Domain of unknown function DUF3338
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030054 cell junction IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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