ENSG00000163362


Homo sapiens

Features
Gene ID: ENSG00000163362
  
Biological name :INAVA
  
Synonyms : INAVA / innate immunity activator / Q3KP66
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 200891048
Gene end: 200915735
  
Corresponding Affymetrix probe sets: 219010_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397255
Ensembl peptide - ENSP00000431682
Ensembl peptide - ENSP00000356311
Ensembl peptide - ENSP00000392105
NCBI entrez gene - 55765     See in Manteia.
RefSeq - XM_011509756
RefSeq - NM_001142569
RefSeq - NM_018265
RefSeq - XM_011509754
RefSeq - XM_011509755
RefSeq Peptide - NP_060735
RefSeq Peptide - NP_001136041
swissprot - E9PK29
swissprot - Q3KP66
swissprot - C9JAT8
Ensembl - ENSG00000163362
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INAVAENSDARG00000078155Danio rerio
 zgc:153953ENSDARG00000070571Danio rerio
 INAVAENSGALG00000044612Gallus gallus
 5730559C18RikENSMUSG00000041605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FRMD4A / Q9P2Q2 / FERM domain containing 4AENSG0000015147433
FRMD4B / Q9Y2L6 / FERM domain containing 4BENSG0000011454125
Q96HB5 / CCDC120 / coiled-coil domain containing 120ENSG0000014714422


Protein motifs (from Interpro)
Interpro ID Name
 IPR021774  Domain of unknown function DUF3338


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0002221 pattern recognition receptor signaling pathway IMP
 biological_processGO:0002367 cytokine production involved in immune response IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IMP
 biological_processGO:0032494 response to peptidoglycan IMP
 biological_processGO:0032495 response to muramyl dipeptide IMP
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IMP
 biological_processGO:0032733 positive regulation of interleukin-10 production IMP
 biological_processGO:0032755 positive regulation of interleukin-6 production IMP
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IMP
 biological_processGO:0034334 adherens junction maintenance IMP
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0060729 intestinal epithelial structure maintenance ISS
 biological_processGO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway IMP
 biological_processGO:1903409 reactive oxygen species biosynthetic process IMP
 cellular_componentGO:0005634 nucleus IMP
 cellular_componentGO:0005737 cytoplasm IMP
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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