ENSG00000115009


Homo sapiens

Features
Gene ID: ENSG00000115009
  
Biological name :CCL20
  
Synonyms : CCL20 / C-C motif chemokine ligand 20 / P78556
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q36.3
Gene start: 227805739
Gene end: 227817564
  
Corresponding Affymetrix probe sets: 205476_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351671
Ensembl peptide - ENSP00000386273
Ensembl peptide - ENSP00000496658
NCBI entrez gene - 6364     See in Manteia.
OMIM - 601960
RefSeq - NM_001130046
RefSeq - NM_004591
RefSeq Peptide - NP_001123518
RefSeq Peptide - NP_004582
swissprot - P78556
Ensembl - ENSG00000115009
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccl20a.3ENSDARG00000101040Danio rerio
 ccl20bENSDARG00000094511Danio rerio
 FP236331.1ENSDARG00000112125Danio rerio
 CCL20ENSGALG00000003003Gallus gallus
 Ccl20ENSMUSG00000026166Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR034133  Chemokine CC, DCCL motif-cointaining domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IDA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050726 positive regulation of interleukin-1 alpha biosynthetic process IEA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IEA
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071223 cellular response to lipoteichoic acid IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0072678 T cell migration IEA
 biological_processGO:0072679 thymocyte migration IEA
 biological_processGO:2000406 positive regulation of T cell migration IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0031731 CCR6 chemokine receptor binding IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000112486 CCR6 / P51684 / C-C motif chemokine receptor 6  / complex / reaction






 

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