ENSG00000115159


Homo sapiens

Features
Gene ID: ENSG00000115159
  
Biological name :GPD2
  
Synonyms : glycerol-3-phosphate dehydrogenase 2 / GPD2 / P43304
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q24.1
Gene start: 156435290
Gene end: 156613735
  
Corresponding Affymetrix probe sets: 210007_s_at (Human Genome U133 Plus 2.0 Array)   211613_s_at (Human Genome U133 Plus 2.0 Array)   225447_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408522
Ensembl peptide - ENSP00000409708
Ensembl peptide - ENSP00000440892
Ensembl peptide - ENSP00000412621
Ensembl peptide - ENSP00000308610
Ensembl peptide - ENSP00000386425
Ensembl peptide - ENSP00000386484
Ensembl peptide - ENSP00000386626
Ensembl peptide - ENSP00000387475
NCBI entrez gene - 2820     See in Manteia.
OMIM - 138430
RefSeq - XM_011510978
RefSeq - XM_011510980
RefSeq - XM_017003830
RefSeq - XM_017003831
RefSeq - NM_001083112
RefSeq - XM_005246469
RefSeq - XM_011510977
RefSeq - NM_000408
RefSeq Peptide - NP_000399
RefSeq Peptide - NP_001076581
swissprot - P43304
swissprot - E7EM56
swissprot - F5GYK7
swissprot - E9PDK4
Ensembl - ENSG00000115159
  
Related genetic diseases (OMIM): 125853 - {Diabetes, type 2, susceptibility to}, 125853
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpd2ENSDARG00000062430Danio rerio
 GPD2ENSGALG00000012543Gallus gallus
 Gpd2ENSMUSG00000026827Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000447  FAD-dependent glycerol-3-phosphate dehydrogenase
 IPR002048  EF-hand domain
 IPR006076  FAD dependent oxidoreductase
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR031656  Alpha-glycerophosphate oxidase, C-terminal
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006072 glycerol-3-phosphate metabolic process IEA
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0006127 glycerophosphate shuttle TAS
 biological_processGO:0019563 glycerol catabolic process IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0009331 glycerol-3-phosphate dehydrogenase complex IEA
 molecular_functionGO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity IEA
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity IEA
 molecular_functionGO:0052591 sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr