ENSG00000115425


Homo sapiens

Features
Gene ID: ENSG00000115425
  
Biological name :PECR
  
Synonyms : PECR / peroxisomal trans-2-enoyl-CoA reductase / Q9BY49
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q35
Gene start: 215996329
Gene end: 216082955
  
Corresponding Affymetrix probe sets: 221142_s_at (Human Genome U133 Plus 2.0 Array)   223619_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265322
Ensembl peptide - ENSP00000395512
NCBI entrez gene - 55825     See in Manteia.
OMIM - 605843
RefSeq - NM_018441
RefSeq - XM_011511478
RefSeq Peptide - NP_060911
swissprot - B4DJS2
swissprot - Q9BY49
Ensembl - ENSG00000115425
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pecrENSDARG00000055976Danio rerio
 PECRENSGALG00000011497Gallus gallus
 PecrENSMUSG00000026189Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DECR1 / Q16698 / 2,4-dienoyl-CoA reductase 1ENSG0000010432530
DECR2 / Q9NUI1 / 2,4-dienoyl-CoA reductase 2ENSG0000024261229


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001561 fatty acid alpha-oxidation TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0033306 phytol metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity EXP


Pathways (from Reactome)
Pathway description
Alpha-oxidation of phytanate
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115425 PECR / Q9BY49 / peroxisomal trans-2-enoyl-CoA reductase  / complex






 

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