ENSG00000104325


Homo sapiens

Features
Gene ID: ENSG00000104325
  
Biological name :DECR1
  
Synonyms : 2,4-dienoyl-CoA reductase 1 / DECR1 / Q16698
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q21.3
Gene start: 90001405
Gene end: 90052092
  
Corresponding Affymetrix probe sets: 202447_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428162
Ensembl peptide - ENSP00000431045
Ensembl peptide - ENSP00000430759
Ensembl peptide - ENSP00000430561
Ensembl peptide - ENSP00000429779
Ensembl peptide - ENSP00000429551
Ensembl peptide - ENSP00000429096
Ensembl peptide - ENSP00000428701
Ensembl peptide - ENSP00000428533
Ensembl peptide - ENSP00000220764
Ensembl peptide - ENSP00000427936
NCBI entrez gene - 1666     See in Manteia.
OMIM - 222745
RefSeq - XM_017013148
RefSeq - XM_017013147
RefSeq - NM_001359
RefSeq - XM_005250808
RefSeq - XM_011516880
RefSeq Peptide - NP_001350
RefSeq Peptide - NP_001317504
swissprot - Q16698
swissprot - H0YAW3
swissprot - E5RJD2
swissprot - E5RID6
swissprot - E5RHR1
swissprot - E5RGS6
swissprot - E5RFV2
swissprot - A0A024R9D7
swissprot - E5RJG7
Ensembl - ENSG00000104325
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 decr1ENSDARG00000003869Danio rerio
 DECR1ENSGALG00000036990Gallus gallus
 Decr1ENSMUSG00000028223Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DECR2 / Q9NUI1 / 2,4-dienoyl-CoA reductase 2ENSG0000024261227
PECR / Q9BY49 / peroxisomal trans-2-enoyl-CoA reductaseENSG0000011542527


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IDA
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion NAS
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H TAS
 molecular_functionGO:0070402 NADPH binding IDA


Pathways (from Reactome)
Pathway description
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104325 DECR1 / Q16698 / 2,4-dienoyl-CoA reductase 1  / complex






 

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