ENSG00000115750


Homo sapiens

Features
Gene ID: ENSG00000115750
  
Biological name :TAF1B
  
Synonyms : Q53T94 / TAF1B / TATA-box binding protein associated factor, RNA polymerase I subunit B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p25.1
Gene start: 9843354
Gene end: 9934416
  
Corresponding Affymetrix probe sets: 214690_at (Human Genome U133 Plus 2.0 Array)   216941_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402955
Ensembl peptide - ENSP00000475608
Ensembl peptide - ENSP00000486572
Ensembl peptide - ENSP00000263663
Ensembl peptide - ENSP00000414184
NCBI entrez gene - 9014     See in Manteia.
OMIM - 604904
RefSeq - XM_011510411
RefSeq - NM_001318976
RefSeq - NM_001318977
RefSeq - NM_005680
RefSeq - XM_011510410
RefSeq Peptide - NP_001305905
RefSeq Peptide - NP_001305906
RefSeq Peptide - NP_005671
swissprot - F8WE32
swissprot - Q53T94
swissprot - U3KQ75
swissprot - F8WDU0
Ensembl - ENSG00000115750
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf1bENSDARG00000028937Danio rerio
 TAF1BENSGALG00000016437Gallus gallus
 Taf1bENSMUSG00000059669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021752  Transcription initiation factor Rrn7, Zinc-finger
 IPR033599  RNA polymerase I transcription initiation factor TAF1B/Rrn7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001188 RNA polymerase I transcriptional preinitiation complex assembly IEA
 biological_processGO:0006351 transcription, DNA-templated NAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006360 transcription by RNA polymerase I IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter TAS
 biological_processGO:0006363 termination of RNA polymerase I transcription TAS
 biological_processGO:0045815 positive regulation of gene expression, epigenetic TAS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005668 RNA polymerase transcription factor SL1 complex IBA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070860 RNA polymerase I core factor complex IEA
 molecular_functionGO:0001164 RNA polymerase I CORE element sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017025 TBP-class protein binding TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr