ENSG00000116251


Homo sapiens

Features
Gene ID: ENSG00000116251
  
Biological name :RPL22
  
Synonyms : P35268 / ribosomal protein L22 / RPL22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.31
Gene start: 6181269
Gene end: 6209389
  
Corresponding Affymetrix probe sets: 208768_x_at (Human Genome U133 Plus 2.0 Array)   214042_s_at (Human Genome U133 Plus 2.0 Array)   220960_x_at (Human Genome U133 Plus 2.0 Array)   221726_at (Human Genome U133 Plus 2.0 Array)   221775_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465313
Ensembl peptide - ENSP00000465763
Ensembl peptide - ENSP00000466013
Ensembl peptide - ENSP00000466502
Ensembl peptide - ENSP00000467247
Ensembl peptide - ENSP00000468274
Ensembl peptide - ENSP00000346088
NCBI entrez gene - 6146     See in Manteia.
OMIM - 180474
RefSeq - NM_000983
RefSeq Peptide - NP_000974
swissprot - P35268
swissprot - K7EJT5
swissprot - K7EKS7
swissprot - K7ELC4
swissprot - K7EMH1
swissprot - K7EP65
swissprot - K7ERI7
Ensembl - ENSG00000116251
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl22ENSDARG00000070437Danio rerio
 Rpl22ENSMUSG00000028936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P5R6 / RPL22L1 / ribosomal protein L22 like 1ENSG0000016358470


Protein motifs (from Interpro)
Interpro ID Name
 IPR002671  Ribosomal protein L22e


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0046632 alpha-beta T cell differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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