ENSG00000116663


Homo sapiens

Features
Gene ID: ENSG00000116663
  
Biological name :FBXO6
  
Synonyms : F-box protein 6 / FBXO6 / Q9NRD1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 11664124
Gene end: 11674354
  
Corresponding Affymetrix probe sets: 231769_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365944
Ensembl peptide - ENSP00000388781
NCBI entrez gene - 26270     See in Manteia.
OMIM - 605647
RefSeq - XM_017001007
RefSeq - NM_018438
RefSeq - XM_005263451
RefSeq - XM_006710571
RefSeq - XM_011541232
RefSeq - XM_005263448
RefSeq - XM_005263449
RefSeq Peptide - NP_060908
swissprot - Q9NRD1
swissprot - J3KQ72
Ensembl - ENSG00000116663
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo44ENSDARG00000022623Danio rerio
 si:dkey-147f3.4ENSDARG00000071029Danio rerio
 si:dkey-147f3.4ENSDARG00000092077Danio rerio
 si:rp71-1k13.6ENSDARG00000115843Danio rerio
 si:rp71-1k13.6ENSDARG00000092166Danio rerio
 zgc:100832ENSDARG00000012035Danio rerio
 zgc:114081ENSDARG00000057899Danio rerio
 zgc:114174ENSDARG00000057884Danio rerio
 zgc:153722ENSDARG00000071044Danio rerio
 zgc:173570ENSDARG00000037645Danio rerio
 ENSGALG00000004646Gallus gallus
 Fbxo6ENSMUSG00000055401Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBXO2 / Q9UK22 / F-box protein 2ENSG0000011666143
FBXO44 / Q9H4M3 / F-box protein 44ENSG0000013287938
FBXO27 / Q8NI29 / F-box protein 27ENSG0000016124337
FBXO17 / Q96EF6 / F-box protein 17ENSG0000026919031
NCCRP1 / Q6ZVX7 / non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)ENSG0000018850525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR007397  F-box associated (FBA) domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint TAS
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006516 glycoprotein catabolic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr