ENSG00000117862


Homo sapiens

Features
Gene ID: ENSG00000117862
  
Biological name :TXNDC12
  
Synonyms : O95881 / thioredoxin domain containing 12 / TXNDC12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 52020131
Gene end: 52056171
  
Corresponding Affymetrix probe sets: 223017_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360688
Ensembl peptide - ENSP00000476401
Ensembl peptide - ENSP00000477120
NCBI entrez gene - 51060     See in Manteia.
OMIM - 609448
RefSeq - NM_015913
RefSeq Peptide - NP_056997
swissprot - O95881
swissprot - V9GY50
swissprot - V9GYV4
Ensembl - ENSG00000117862
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txndc12ENSDARG00000038980Danio rerio
 TXNDC12ENSGALG00000010569Gallus gallus
 Q9CQU0ENSMUSG00000028567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGR3 / Q8TD06 / anterior gradient 3, protein disulphide isomerase family memberENSG0000017346733
AGR2 / O95994 / anterior gradient 2, protein disulphide isomerase family memberENSG0000010654133


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily
 IPR037462  ERp19


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019153 protein-disulfide reductase (glutathione) activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr