ENSG00000106541


Homo sapiens

Features
Gene ID: ENSG00000106541
  
Biological name :AGR2
  
Synonyms : AGR2 / anterior gradient 2, protein disulphide isomerase family member / O95994
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.1
Gene start: 16791811
Gene end: 16833433
  
Corresponding Affymetrix probe sets: 209173_at (Human Genome U133 Plus 2.0 Array)   228969_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386025
Ensembl peptide - ENSP00000414806
Ensembl peptide - ENSP00000411969
Ensembl peptide - ENSP00000391490
NCBI entrez gene - 10551     See in Manteia.
OMIM - 606358
RefSeq - XM_005249581
RefSeq - NM_006408
RefSeq Peptide - NP_006399
swissprot - H7C3Z9
swissprot - C9J3E2
swissprot - O95994
swissprot - Q4JM46
swissprot - B5MC07
Ensembl - ENSG00000106541
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agr2ENSDARG00000070480Danio rerio
 AGR2ENSGALG00000010825Gallus gallus
 Agr2ENSMUSG00000020581Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGR3 / Q8TD06 / anterior gradient 3, protein disulphide isomerase family memberENSG0000017346759
O95881 / TXNDC12 / thioredoxin domain containing 12ENSG0000011786232


Protein motifs (from Interpro)
Interpro ID Name
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IMP
 biological_processGO:0048546 digestive tract morphogenesis IEA
 biological_processGO:0048639 positive regulation of developmental growth IEA
 biological_processGO:0060480 lung goblet cell differentiation IEA
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0070254 mucus secretion IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IMP
 biological_processGO:1903896 positive regulation of IRE1-mediated unfolded protein response IDA
 biological_processGO:1903899 positive regulation of PERK-mediated unfolded protein response IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 molecular_functionGO:0002162 dystroglycan binding IDA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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