ENSDARG00000070480


Danio rerio

Features
Gene ID: ENSDARG00000070480
  
Biological name :agr2
  
Synonyms : agr2 / anterior gradient 2 / Q5RZ65
  
Possible biological names infered from orthology : Anterior gradient / anterior gradient 2, protein disulphide isomerase family member / O88312 / O95994
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 30400372
Gene end: 30404096
  
Corresponding Affymetrix probe sets: Dr.25277.1.S1_at (Zebrafish Array)   NM_001012481_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000094251
Ensembl peptide - ENSDARP00000157253
NCBI entrez gene - 335616     See in Manteia.
RefSeq - NM_001012481
RefSeq Peptide - NP_001012499
swissprot - Q5RZ65
ZFIN ID - ZDB-GENE-050417-214
Ensembl - ENSDARG00000070480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AGR2ENSGALG00000010825Gallus gallus
 AGR2ENSG00000106541Homo sapiens
 Agr2ENSMUSG00000020581Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
agr1 / anterior gradient 1ENSDARG0000006068251
txndc12 / thioredoxin domain containing 12 (endoplasmic reticulum) / O95881* / Q9CQU0* / thioredoxin domain containing 12*ENSDARG0000003898030


Protein motifs (from Interpro)
Interpro ID Name
 IPR012336  Thioredoxin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010811 positive regulation of cell-substrate adhesion ISS
 biological_processGO:0060548 negative regulation of cell death IBA
 biological_processGO:0060575 intestinal epithelial cell differentiation IMP
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 molecular_functionGO:0002162 dystroglycan binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009094 goblet cell goblet cell cellular quality , abnormal
goblet cell immature , abnormal
goblet cell secretory granule decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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