ENSMUSG00000028567


Mus musculus

Features
Gene ID: ENSMUSG00000028567
  
Biological name :Txndc12
  
Synonyms : Q9CQU0 / thioredoxin domain containing 12 (endoplasmic reticulum) / Txndc12
  
Possible biological names infered from orthology : O95881 / thioredoxin domain containing 12
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C7
Gene start: 108834601
Gene end: 108862127
  
Corresponding Affymetrix probe sets: 10506870 (MoGene1.0st)   10339290 (MoGene1.0st)   10340074 (MoGene1.0st)   10340580 (MoGene1.0st)   10341051 (MoGene1.0st)   10341657 (MoGene1.0st)   10341663 (MoGene1.0st)   10342947 (MoGene1.0st)   10343741 (MoGene1.0st)   10339417 (MoGene1.0st)   10340302 (MoGene1.0st)   10341259 (MoGene1.0st)   10341406 (MoGene1.0st)   10341545 (MoGene1.0st)   10343089 (MoGene1.0st)   10343375 (MoGene1.0st)   1415738_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030296
NCBI entrez gene - 66073     See in Manteia.
MGI - MGI:1913323
RefSeq - NM_025334
RefSeq Peptide - NP_079610
swissprot - Q9CQU0
Ensembl - ENSMUSG00000028567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txndc12ENSDARG00000038980Danio rerio
 TXNDC12ENSGALG00000010569Gallus gallus
 O95881ENSG00000117862Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Agr3 / Q8R3W7 / Anterior gradient protein 3 / Q8TD06* / anterior gradient 3, protein disulphide isomerase family member*ENSMUSG0000003623137
Agr2 / O88312 / Anterior gradient / O95994* / anterior gradient 2, protein disulphide isomerase family member*ENSMUSG0000002058133


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily
 IPR037462  ERp19


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060548 negative regulation of cell death IBA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen ISO
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019153 protein-disulfide reductase (glutathione) activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mecp2tm1.1Irsf/Y
Genetic Background: involves: 129S/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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