ENSG00000119203


Homo sapiens

Features
Gene ID: ENSG00000119203
  
Biological name :CPSF3
  
Synonyms : cleavage and polyadenylation specific factor 3 / CPSF3 / Q9UKF6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p25.1
Gene start: 9423568
Gene end: 9473101
  
Corresponding Affymetrix probe sets: 225082_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419744
Ensembl peptide - ENSP00000238112
Ensembl peptide - ENSP00000418957
NCBI entrez gene - 51692     See in Manteia.
OMIM - 606029
RefSeq - NM_001321835
RefSeq - NM_001321833
RefSeq - NM_001321834
RefSeq - NM_001321836
RefSeq - NM_016207
RefSeq Peptide - NP_001308764
RefSeq Peptide - NP_001308765
RefSeq Peptide - NP_057291
RefSeq Peptide - NP_001308763
RefSeq Peptide - NP_001308762
swissprot - C9JZH6
swissprot - Q9UKF6
swissprot - G5E9W3
Ensembl - ENSG00000119203
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpsf3ENSDARG00000027649Danio rerio
 CPSF3ENSGALG00000016424Gallus gallus
 Cpsf3ENSMUSG00000054309Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INTS11 / Q5TA45 / integrator complex subunit 11ENSG0000012705429


Protein motifs (from Interpro)
Interpro ID Name
 IPR001279  Metallo-beta-lactamase
 IPR011108  Zn-dependent metallo-hydrolase, RNA specificity domain
 IPR021718  Pre-mRNA 3"-end-processing endonuclease polyadenylation factor C-term
 IPR022712  Beta-Casp domain
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006378 mRNA polyadenylation TAS
 biological_processGO:0006379 mRNA cleavage TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006398 mRNA 3"-end processing by stem-loop binding and cleavage IEA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004521 endoribonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008409 5"-3" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr