ENSG00000119397


Homo sapiens

Features
Gene ID: ENSG00000119397
  
Biological name :CNTRL
  
Synonyms : centriolin / CNTRL / Q7Z7A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.2
Gene start: 121074863
Gene end: 121177610
  
Corresponding Affymetrix probe sets: 205642_at (Human Genome U133 Plus 2.0 Array)   242916_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481072
Ensembl peptide - ENSP00000238341
Ensembl peptide - ENSP00000362972
Ensembl peptide - ENSP00000413014
Ensembl peptide - ENSP00000362950
Ensembl peptide - ENSP00000362953
Ensembl peptide - ENSP00000362956
Ensembl peptide - ENSP00000362962
NCBI entrez gene - 11064     See in Manteia.
OMIM - 605496
RefSeq - XM_017014229
RefSeq - NM_001330762
RefSeq - NM_007018
RefSeq - XM_011518173
RefSeq - XM_017014223
RefSeq - XM_017014224
RefSeq - XM_017014225
RefSeq - XM_017014226
RefSeq - XM_017014227
RefSeq - XM_017014228
RefSeq - XM_005251679
RefSeq - XM_006716940
RefSeq - XM_006716942
RefSeq - XM_006716944
RefSeq - XM_011518166
RefSeq - XM_011518167
RefSeq - XM_011518168
RefSeq - XM_011518169
RefSeq - XM_011518170
RefSeq - XM_011518172
RefSeq Peptide - NP_008949
RefSeq Peptide - NP_001317691
swissprot - Q5JVD3
swissprot - Q5JVD6
swissprot - Q7Z7A1
swissprot - Q5JVD5
swissprot - Q5JVD1
Ensembl - ENSG00000119397
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cntrlENSDARG00000088492Danio rerio
 CNTRLENSGALG00000001513Gallus gallus
 CntrlENSMUSG00000057110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRCC1 / Q9C099 / leucine rich repeat and coiled-coil centrosomal protein 1ENSG000001337399


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR028640  Centriolin
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0090543 Flemming body IEA
 cellular_componentGO:0120103 centriolar subdistal appendage IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000119397 CNTRL / Q7Z7A1 / centriolin  / complex






 

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