ENSG00000119608


Homo sapiens

Features
Gene ID: ENSG00000119608
  
Biological name :PROX2
  
Synonyms : prospero homeobox 2 / PROX2 / Q3B8N5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q24.3
Gene start: 74852871
Gene end: 74871940
  
Corresponding Affymetrix probe sets: 234804_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478947
Ensembl peptide - ENSP00000451223
Ensembl peptide - ENSP00000451463
NCBI entrez gene - 283571     See in Manteia.
OMIM - 615094
RefSeq - XM_005267543
RefSeq - NM_001080408
RefSeq - NM_001243007
RefSeq Peptide - NP_001073877
RefSeq Peptide - NP_001229936
swissprot - A0A0G2JMC2
swissprot - G3V3G0
swissprot - Q3B8N5
Ensembl - ENSG00000119608
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prox2ENSDARG00000041952Danio rerio
 ENSGALG00000023113Gallus gallus
 Prox2ENSMUSG00000042320Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PROX1 / Q92786 / prospero homeobox 1ENSG0000011770735


Protein motifs (from Interpro)
Interpro ID Name
 IPR009057  Homeobox-like domain superfamily
 IPR023082  Homeo-prospero domain
 IPR037131  Homeo-prospero domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0001946 lymphangiogenesis IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0055007 cardiac muscle cell differentiation IBA
 biological_processGO:0060836 lymphatic endothelial cell differentiation IBA
 biological_processGO:0070309 lens fiber cell morphogenesis IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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