ENSG00000120337


Homo sapiens

Features
Gene ID: ENSG00000120337
  
Biological name :TNFSF18
  
Synonyms : Q9UNG2 / TNFSF18 / TNF superfamily member 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.1
Gene start: 173039960
Gene end: 173050963
  
Corresponding Affymetrix probe sets: 221371_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385470
NCBI entrez gene - 8995     See in Manteia.
OMIM - 603898
RefSeq - NM_005092
RefSeq Peptide - NP_005083
swissprot - A0A0U5JXL4
swissprot - Q9UNG2
Ensembl - ENSG00000120337
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7TS55ENSMUSG00000066755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002309 T cell proliferation involved in immune response IBA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002687 positive regulation of leukocyte migration IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IBA
 biological_processGO:0042129 regulation of T cell proliferation IBA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0045785 positive regulation of cell adhesion IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032813 tumor necrosis factor receptor superfamily binding ISS
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000186891 Q9Y5U5 / TNFRSF18 / TNF receptor superfamily member 18  / complex / reaction






 

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