ENSG00000123213


Homo sapiens

Features
Gene ID: ENSG00000123213
  
Biological name :NLN
  
Synonyms : neurolysin / NLN / Q9BYT8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q12.3
Gene start: 65722196
Gene end: 65871725
  
Corresponding Affymetrix probe sets: 224063_at (Human Genome U133 Plus 2.0 Array)   225942_at (Human Genome U133 Plus 2.0 Array)   225943_at (Human Genome U133 Plus 2.0 Array)   225944_at (Human Genome U133 Plus 2.0 Array)   228797_at (Human Genome U133 Plus 2.0 Array)   234762_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422822
Ensembl peptide - ENSP00000427417
Ensembl peptide - ENSP00000426959
Ensembl peptide - ENSP00000423214
Ensembl peptide - ENSP00000370372
NCBI entrez gene - 57486     See in Manteia.
OMIM - 611530
RefSeq - XM_017009673
RefSeq - NM_020726
RefSeq - XM_005248559
RefSeq - XM_006714661
RefSeq Peptide - NP_065777
swissprot - E9PCB6
swissprot - Q9BYT8
swissprot - D6R9Y0
swissprot - H0YAF7
swissprot - H0YAK4
Ensembl - ENSG00000123213
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nlnENSDARG00000019233Danio rerio
 NLNENSGALG00000014769Gallus gallus
 NlnENSMUSG00000021710Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
THOP1 / P52888 / thimet oligopeptidase 1ENSG0000017200961


Protein motifs (from Interpro)
Interpro ID Name
 IPR001567  Peptidase M3A/M3B catalytic domain
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR024080  Neurolysin/Thimet oligopeptidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006111 regulation of gluconeogenesis IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006518 peptide metabolic process IBA
 biological_processGO:1902809 regulation of skeletal muscle fiber differentiation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000133636 NTS / P30990 / neurotensin  / reaction






 

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