ENSG00000124134


Homo sapiens

Features
Gene ID: ENSG00000124134
  
Biological name :KCNS1
  
Synonyms : KCNS1 / potassium voltage-gated channel modifier subfamily S member 1 / Q96KK3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45092310
Gene end: 45101112
  
Corresponding Affymetrix probe sets: 207366_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445595
Ensembl peptide - ENSP00000307694
NCBI entrez gene - 3787     See in Manteia.
OMIM - 602905
RefSeq - XM_017027846
RefSeq - NM_001322799
RefSeq - NM_002251
RefSeq Peptide - NP_001309728
RefSeq Peptide - NP_002242
swissprot - Q96KK3
swissprot - A2RUL8
Ensembl - ENSG00000124134
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-43k4.5ENSDARG00000026084Danio rerio
 KCNS1ENSGALG00000004074Gallus gallus
 Kcns1ENSMUSG00000040164Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNS2 / Q9ULS6 / potassium voltage-gated channel modifier subfamily S member 2ENSG0000015648645
KCNS3 / Q9BQ31 / potassium voltage-gated channel modifier subfamily S member 3ENSG0000017074542
KCNB1 / Q14721 / potassium voltage-gated channel subfamily B member 1ENSG0000015844535
KCNB2 / Q92953 / potassium voltage-gated channel subfamily B member 2ENSG0000018267434
KCNV1 / Q6PIU1 / potassium voltage-gated channel modifier subfamily V member 1ENSG0000016479434
KCNV2 / Q8TDN2 / potassium voltage-gated channel modifier subfamily V member 2ENSG0000016826333
KCNG2 / Q9UJ96 / potassium voltage-gated channel modifier subfamily G member 2ENSG0000017834230
KCNG4 / Q8TDN1 / potassium voltage-gated channel modifier subfamily G member 4ENSG0000016841830
KCNG1 / Q9UIX4 / potassium voltage-gated channel modifier subfamily G member 1ENSG0000002655929
KCNF1 / Q9H3M0 / potassium voltage-gated channel modifier subfamily F member 1ENSG0000016297529
KCNG3 / Q8TAE7 / potassium voltage-gated channel modifier subfamily G member 3ENSG0000017112626


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003971  Potassium channel, voltage dependent, Kv9
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1902259 regulation of delayed rectifier potassium channel activity ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IDA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015459 potassium channel regulator activity TAS


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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