ENSG00000170745


Homo sapiens

Features
Gene ID: ENSG00000170745
  
Biological name :KCNS3
  
Synonyms : KCNS3 / potassium voltage-gated channel modifier subfamily S member 3 / Q9BQ31
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p24.2
Gene start: 17877847
Gene end: 18361616
  
Corresponding Affymetrix probe sets: 205968_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000400098
Ensembl peptide - ENSP00000305824
Ensembl peptide - ENSP00000385968
NCBI entrez gene - 3790     See in Manteia.
OMIM - 603888
RefSeq - XM_017004059
RefSeq - NM_001282428
RefSeq - NM_002252
RefSeq - XM_011532825
RefSeq Peptide - NP_002243
RefSeq Peptide - NP_001269357
swissprot - Q9BQ31
swissprot - C9J187
Ensembl - ENSG00000170745
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcns3aENSDARG00000006891Danio rerio
 KCNS3ENSGALG00000016470Gallus gallus
 Kcns3ENSMUSG00000043673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNS2 / Q9ULS6 / potassium voltage-gated channel modifier subfamily S member 2ENSG0000015648652
KCNS1 / Q96KK3 / potassium voltage-gated channel modifier subfamily S member 1ENSG0000012413445
KCNB1 / Q14721 / potassium voltage-gated channel subfamily B member 1ENSG0000015844543
KCNB2 / Q92953 / potassium voltage-gated channel subfamily B member 2ENSG0000018267442
KCNV1 / Q6PIU1 / potassium voltage-gated channel modifier subfamily V member 1ENSG0000016479440
KCNV2 / Q8TDN2 / potassium voltage-gated channel modifier subfamily V member 2ENSG0000016826334
KCNG1 / Q9UIX4 / potassium voltage-gated channel modifier subfamily G member 1ENSG0000002655933
KCNF1 / Q9H3M0 / potassium voltage-gated channel modifier subfamily F member 1ENSG0000016297532
KCNG4 / Q8TDN1 / potassium voltage-gated channel modifier subfamily G member 4ENSG0000016841832
KCNG2 / Q9UJ96 / potassium voltage-gated channel modifier subfamily G member 2ENSG0000017834230
KCNG3 / Q8TAE7 / potassium voltage-gated channel modifier subfamily G member 3ENSG0000017112628


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003971  Potassium channel, voltage dependent, Kv9
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015459 potassium channel regulator activity TAS


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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