ENSG00000182674


Homo sapiens

Features
Gene ID: ENSG00000182674
  
Biological name :KCNB2
  
Synonyms : KCNB2 / potassium voltage-gated channel subfamily B member 2 / Q92953
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q21.11
Gene start: 72537391
Gene end: 72938349
  
Corresponding Affymetrix probe sets: 208123_at (Human Genome U133 Plus 2.0 Array)   208172_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430846
NCBI entrez gene - 9312     See in Manteia.
OMIM - 607738
RefSeq - NM_004770
RefSeq Peptide - NP_004761
swissprot - Q92953
Ensembl - ENSG00000182674
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnb2ENSDARG00000038862Danio rerio
 KCNB2ENSDARG00000088842Danio rerio
 KCNB2ENSGALG00000031693Gallus gallus
 Kcnb2ENSMUSG00000092083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNB1 / Q14721 / potassium voltage-gated channel subfamily B member 1ENSG0000015844561
KCNV1 / Q6PIU1 / potassium voltage-gated channel modifier subfamily V member 1ENSG0000016479423
KCNS3 / Q9BQ31 / potassium voltage-gated channel modifier subfamily S member 3ENSG0000017074523
KCNF1 / Q9H3M0 / potassium voltage-gated channel modifier subfamily F member 1ENSG0000016297521
KCNS2 / Q9ULS6 / potassium voltage-gated channel modifier subfamily S member 2ENSG0000015648621
KCNG1 / Q9UIX4 / potassium voltage-gated channel modifier subfamily G member 1ENSG0000002655921
KCNS1 / Q96KK3 / potassium voltage-gated channel modifier subfamily S member 1ENSG0000012413420
KCNG4 / Q8TDN1 / potassium voltage-gated channel modifier subfamily G member 4ENSG0000016841820
KCNG2 / Q9UJ96 / potassium voltage-gated channel modifier subfamily G member 2ENSG0000017834219
KCNV2 / Q8TDN2 / potassium voltage-gated channel modifier subfamily V member 2ENSG0000016826319
KCNG3 / Q8TAE7 / potassium voltage-gated channel modifier subfamily G member 3ENSG0000017112618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003973  Potassium channel, voltage dependent, Kv2
 IPR005821  Ion transport domain
 IPR005826  Potassium channel, voltage dependent, Kv2.2
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0006940 regulation of smooth muscle contraction TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISS


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr