ENSMUSG00000092083


Mus musculus

Features
Gene ID: ENSMUSG00000092083
  
Biological name :Kcnb2
  
Synonyms : A6H8H5 / Kcnb2 / Potassium voltage-gated channel subfamily B member 2
  
Possible biological names infered from orthology : Q92953
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: A3
Gene start: 15287254
Gene end: 15723750
  
Corresponding Affymetrix probe sets: 10344935 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000126656
Ensembl peptide - ENSMUSP00000135382
NCBI entrez gene - 98741     See in Manteia.
MGI - MGI:99632
RefSeq - XM_006495597
RefSeq - NM_001098528
RefSeq - XM_006495595
RefSeq - XM_006495596
RefSeq Peptide - NP_001091998
swissprot - A6H8H5
Ensembl - ENSMUSG00000092083
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnb2ENSDARG00000038862Danio rerio
 KCNB2ENSDARG00000088842Danio rerio
 KCNB2ENSGALG00000031693Gallus gallus
 KCNB2ENSG00000182674Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnb1 / Q03717 / Potassium voltage-gated channel subfamily B member 1 / Q14721*ENSMUSG0000005055660
Kcnv1 / Q8BZN2 / Potassium voltage-gated channel subfamily V member 1 / Q6PIU1* / potassium voltage-gated channel modifier subfamily V member 1*ENSMUSG0000002234223
Kcns3 / Q8BQZ8 / Potassium voltage-gated channel subfamily S member 3 / Q9BQ31* / potassium voltage-gated channel modifier subfamily S member 3*ENSMUSG0000004367323
Kcns2 / O35174 / Potassium voltage-gated channel subfamily S member 2 / Q9ULS6* / potassium voltage-gated channel modifier subfamily S member 2*ENSMUSG0000005096321
Kcng1 / A2BDX4 / Potassium voltage-gated channel subfamily G member 1 / Q9UIX4* / potassium voltage-gated channel modifier subfamily G member 1*ENSMUSG0000007457521
Kcnf1 / potassium voltage-gated channel modifier subfamily F member 1 / Q9H3M0*ENSMUSG0000005172621
Kcnv2 / Q8CFS6 / Potassium voltage-gated channel subfamily V member 2 / Q8TDN2* / potassium voltage-gated channel modifier subfamily V member 2*ENSMUSG0000004729820
Kcng4 / Q80XM3 / Potassium voltage-gated channel subfamily G member 4 / Q8TDN1* / potassium voltage-gated channel modifier subfamily G member 4*ENSMUSG0000004524620
Kcns1 / O35173 / Potassium voltage-gated channel subfamily S member 1 / Q96KK3* / potassium voltage-gated channel modifier subfamily S member 1*ENSMUSG0000004016419
Kcng3 / P59053 / Potassium voltage-gated channel subfamily G member 3 / Q8TAE7* / potassium voltage-gated channel modifier subfamily G member 3*ENSMUSG0000004505318
Kcng2 / potassium voltage-gated channel modifier subfamily G member 2 / Q9UJ96*ENSMUSG0000005985218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003973  Potassium channel, voltage dependent, Kv2
 IPR005821  Ion transport domain
 IPR005826  Potassium channel, voltage dependent, Kv2.2
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport ISS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0008076 voltage-gated potassium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity ISS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISS


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Frem2b2b1562Clo/Frem2b2b1562Clo
Genetic Background: C57BL/6J-Frem2b2b1562Clo

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Frem2b2b1562Clo/Frem2b2b1562Clo
Genetic Background: C57BL/6J-Frem2b2b1562Clo

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Frem2b2b1562Clo/Frem2b2b1562Clo
Genetic Background: C57BL/6J-Frem2b2b1562Clo

 MP:0001501 abnormal sleep pattern "deviation from the normal wake/sleep cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Frem2b2b1562Clo/Frem2b2b1562Clo
Genetic Background: C57BL/6J-Frem2b2b1562Clo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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