ENSMUSG00000022342


Mus musculus

Features
Gene ID: ENSMUSG00000022342
  
Biological name :Kcnv1
  
Synonyms : Kcnv1 / Potassium voltage-gated channel subfamily V member 1 / Q8BZN2
  
Possible biological names infered from orthology : potassium voltage-gated channel modifier subfamily V member 1 / Q6PIU1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B3.3
Gene start: 45106284
Gene end: 45114920
  
Corresponding Affymetrix probe sets: 10428443 (MoGene1.0st)   1429741_at (Mouse Genome 430 2.0 Array)   1439333_at (Mouse Genome 430 2.0 Array)   1453273_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022967
NCBI entrez gene - 67498     See in Manteia.
MGI - MGI:1914748
RefSeq - NM_026200
RefSeq - XM_006521297
RefSeq Peptide - NP_080476
swissprot - Q8BZN2
Ensembl - ENSMUSG00000022342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNV1ENSDARG00000070092Danio rerio
 ENSGALG00000031449Gallus gallus
 KCNV1ENSG00000164794Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnb1 / Q03717 / Potassium voltage-gated channel subfamily B member 1 / Q14721*ENSMUSG0000005055642
Kcnb2 / A6H8H5 / Potassium voltage-gated channel subfamily B member 2 / Q92953*ENSMUSG0000009208342
Kcns2 / O35174 / Potassium voltage-gated channel subfamily S member 2 / Q9ULS6* / potassium voltage-gated channel modifier subfamily S member 2*ENSMUSG0000005096340
Kcns3 / Q8BQZ8 / Potassium voltage-gated channel subfamily S member 3 / Q9BQ31* / potassium voltage-gated channel modifier subfamily S member 3*ENSMUSG0000004367339
Kcns1 / O35173 / Potassium voltage-gated channel subfamily S member 1 / Q96KK3* / potassium voltage-gated channel modifier subfamily S member 1*ENSMUSG0000004016435
Kcnv2 / Q8CFS6 / Potassium voltage-gated channel subfamily V member 2 / Q8TDN2* / potassium voltage-gated channel modifier subfamily V member 2*ENSMUSG0000004729834
Kcng1 / A2BDX4 / Potassium voltage-gated channel subfamily G member 1 / Q9UIX4* / potassium voltage-gated channel modifier subfamily G member 1*ENSMUSG0000007457532
Kcnf1 / potassium voltage-gated channel modifier subfamily F member 1 / Q9H3M0*ENSMUSG0000005172631
Kcng2 / potassium voltage-gated channel modifier subfamily G member 2 / Q9UJ96*ENSMUSG0000005985231
Kcng4 / Q80XM3 / Potassium voltage-gated channel subfamily G member 4 / Q8TDN1* / potassium voltage-gated channel modifier subfamily G member 4*ENSMUSG0000004524630
Kcng3 / P59053 / Potassium voltage-gated channel subfamily G member 3 / Q8TAE7* / potassium voltage-gated channel modifier subfamily G member 3*ENSMUSG0000004505330


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003970  Potassium channel, voltage dependent, Kv8.1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000743 muscle spasms "muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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