ENSG00000124191


Homo sapiens

Features
Gene ID: ENSG00000124191
  
Biological name :TOX2
  
Synonyms : Q96NM4 / TOX2 / TOX high mobility group box family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.12
Gene start: 43914864
Gene end: 44069616
  
Corresponding Affymetrix probe sets: 228737_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362090
Ensembl peptide - ENSP00000344724
Ensembl peptide - ENSP00000350849
Ensembl peptide - ENSP00000390278
Ensembl peptide - ENSP00000390876
NCBI entrez gene - 84969     See in Manteia.
OMIM - 611163
RefSeq - XM_017028109
RefSeq - NM_001098796
RefSeq - NM_001098797
RefSeq - NM_001098798
RefSeq - NM_032883
RefSeq - XM_006723884
RefSeq Peptide - NP_001092268
RefSeq Peptide - NP_116272
RefSeq Peptide - NP_001092266
RefSeq Peptide - NP_001092267
swissprot - Q5JYD4
swissprot - Q96NM4
Ensembl - ENSG00000124191
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tox2ENSDARG00000100055Danio rerio
 ENSGALG00000003106Gallus gallus
 Tox2ENSMUSG00000074607Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TOX / O94900 / thymocyte selection associated high mobility group boxENSG0000019884644
TOX3 / O15405 / TOX high mobility group box family member 3ENSG0000010346039
TOX4 / O94842 / TOX high mobility group box family member 4ENSG0000009220336
SSRP1 / Q08945 / structure specific recognition protein 1ENSG0000014913619


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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