ENSG00000103460


Homo sapiens

Features
Gene ID: ENSG00000103460
  
Biological name :TOX3
  
Synonyms : O15405 / TOX3 / TOX high mobility group box family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q12.1
Gene start: 52438005
Gene end: 52547802
  
Corresponding Affymetrix probe sets: 214774_x_at (Human Genome U133 Plus 2.0 Array)   215108_x_at (Human Genome U133 Plus 2.0 Array)   216623_x_at (Human Genome U133 Plus 2.0 Array)   230745_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000219746
Ensembl peptide - ENSP00000385705
Ensembl peptide - ENSP00000457401
Ensembl peptide - ENSP00000463843
NCBI entrez gene - 27324     See in Manteia.
OMIM - 611416
RefSeq - XM_017023142
RefSeq - NM_001080430
RefSeq - NM_001146188
RefSeq - XM_005255892
RefSeq - XM_011523002
RefSeq Peptide - NP_001139660
RefSeq Peptide - NP_001073899
swissprot - J3QQQ6
swissprot - O15405
swissprot - H3BTZ9
Ensembl - ENSG00000103460
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tox3ENSDARG00000073957Danio rerio
 TOX3ENSGALG00000034649Gallus gallus
 Tox3ENSMUSG00000043668Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TOX / O94900 / thymocyte selection associated high mobility group boxENSG0000019884644
TOX4 / O94842 / TOX high mobility group box family member 4ENSG0000009220337
TOX2 / Q96NM4 / TOX high mobility group box family member 2ENSG0000012419134
SSRP1 / Q08945 / structure specific recognition protein 1ENSG0000014913617


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0042981 regulation of apoptotic process IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0034056 estrogen response element binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0051219 phosphoprotein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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