ENSG00000149136


Homo sapiens

Features
Gene ID: ENSG00000149136
  
Biological name :SSRP1
  
Synonyms : Q08945 / SSRP1 / structure specific recognition protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.1
Gene start: 57325985
Gene end: 57335877
  
Corresponding Affymetrix probe sets: 200956_s_at (Human Genome U133 Plus 2.0 Array)   200957_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000278412
Ensembl peptide - ENSP00000489564
Ensembl peptide - ENSP00000434546
Ensembl peptide - ENSP00000431154
NCBI entrez gene - 6749     See in Manteia.
OMIM - 604328
RefSeq - XM_017018180
RefSeq - NM_003146
RefSeq Peptide - NP_003137
swissprot - A0A0U1RRK2
swissprot - A0A024R4Z6
swissprot - E9PPZ7
swissprot - Q08945
swissprot - E9PMD4
Ensembl - ENSG00000149136
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssrp1aENSDARG00000037397Danio rerio
 ssrp1bENSDARG00000016994Danio rerio
 SSRP1ENSGALG00000007520Gallus gallus
 Ssrp1ENSMUSG00000027067Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TOX3 / O15405 / TOX high mobility group box family member 3ENSG0000010346014
TOX4 / O94842 / TOX high mobility group box family member 4ENSG0000009220313
TOX2 / Q96NM4 / TOX high mobility group box family member 2ENSG0000012419113
TOX / O94900 / thymocyte selection associated high mobility group boxENSG0000019884613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000969  Structure-specific recognition protein
 IPR009071  High mobility group box domain
 IPR011993  PH-like domain superfamily
 IPR013719  Domain of unknown function DUF1747
 IPR024954  SSRP1 domain
 IPR035417  FACT complex subunit POB3-like, N-terminal PH domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000092201 Q9Y5B9 / SUPT16H / SPT16 homolog, facilitates chromatin remodeling subunit  / complex / reaction
 ENSG00000101266 P68400 / CSNK2A1 / casein kinase 2 alpha 1  / complex / reaction
 ENSG00000204435 CSNK2B / P67870 / casein kinase 2 beta  / reaction / complex
 ENSG00000070770 P19784 / CSNK2A2 / casein kinase 2 alpha 2  / complex / reaction






 

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