ENSG00000092201


Homo sapiens

Features
Gene ID: ENSG00000092201
  
Biological name :SUPT16H
  
Synonyms : Q9Y5B9 / SPT16 homolog, facilitates chromatin remodeling subunit / SUPT16H
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 21351472
Gene end: 21384266
  
Corresponding Affymetrix probe sets: 217815_at (Human Genome U133 Plus 2.0 Array)   233827_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216297
Ensembl peptide - ENSP00000450910
Ensembl peptide - ENSP00000451517
Ensembl peptide - ENSP00000452259
NCBI entrez gene - 11198     See in Manteia.
OMIM - 605012
RefSeq - XM_011536381
RefSeq - NM_007192
RefSeq Peptide - NP_009123
swissprot - G3V5A4
swissprot - G3V2X0
swissprot - Q9Y5B9
swissprot - G3V401
Ensembl - ENSG00000092201
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 supt16hENSDARG00000079949Danio rerio
 Supt16ENSMUSG00000035726Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000994  Peptidase M24
 IPR011989  Armadillo-like helical
 IPR013719  Domain of unknown function DUF1747
 IPR013953  FACT complex subunit Spt16p/Cdc68p
 IPR029148  FACT complex subunit Spt16, N-terminal lobe domain
 IPR029149  Creatinase/Aminopeptidase P/Spt16, N-terminal
 IPR033825  FACT complex subunit SPT16
 IPR036005  Creatinase/aminopeptidase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006337 nucleosome disassembly TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation TAS
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0034724 DNA replication-independent nucleosome organization IBA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0035101 FACT complex IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031491 nucleosome binding IBA
 molecular_functionGO:0042393 histone binding IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000070770 P19784 / CSNK2A2 / casein kinase 2 alpha 2  / complex / reaction
 ENSG00000149136 SSRP1 / Q08945 / structure specific recognition protein 1  / complex / reaction
 ENSG00000101266 P68400 / CSNK2A1 / casein kinase 2 alpha 1  / complex / reaction
 ENSG00000204435 CSNK2B / P67870 / casein kinase 2 beta  / reaction / complex






 

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